Neco Model Questions Vol1 2023 Biology Question 20

Practice objective / multiple choice question 20 from the 2023 Neco Model Questions Vol1 Biology examination.

Neco Model Questions Vol1 2023 Biology Objective / Multiple Choice Hard Difficulty
Question 20 NECO_MODEL_QUESTIONS_VOL1 • 2023 • BIOLOGY • objective

A drug follows first‑order elimination with a half‑life of \(8\) h and a volume of distribution of \(40\) L. To achieve a target plasma concentration of \(15\) mg L\(^{-1}\), a loading dose is given, followed by equal maintenance doses every \(8\) h to maintain steady‑state. Calculate (a) the required loading dose in milligrams, and (b) the maintenance dose in milligrams (rounded to the nearest milligram). Use \(\ln 2 = 0.693\).

Answer Options

Correct Answer A. Loading dose: 600 mg; Maintenance dose: 416 mg
B. Loading dose: 600 mg; Maintenance dose: 450 mg
C. Loading dose: 640 mg; Maintenance dose: 384 mg
D. Loading dose: 560 mg; Maintenance dose: 416 mg
Correct Answer
A
Correct Option:
Loading dose: 600 mg; Maintenance dose: 416 mg

About This Question

This is Neco Model Questions Vol1 2023 Biology Question 20. It is one of the objective questions from the 2023 Neco Model Questions Vol1 Biology examination.

Difficulty level: Hard .

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