Neco Model Questions Vol1 2019 Biology Question 33

Practice objective / multiple choice question 33 from the 2019 Neco Model Questions Vol1 Biology examination.

Neco Model Questions Vol1 2019 Biology Objective / Multiple Choice Hard Difficulty
Question 33 NECO_MODEL_QUESTIONS_VOL1 • 2019 • BIOLOGY • objective

A diploid human population living at sea level has the following blood‑gas parameters: atmospheric pressure 101.3 kPa, oxygen fraction 21 %, hemoglobin concentration 150 g L⁻¹, and P₅₀ = 26 mmHg. A second population lives at 3000 m altitude where atmospheric pressure is 70 kPa; the oxygen fraction is the same, hemoglobin concentration is increased by an unknown amount, and P₅₀ is reduced to 24 mmHg because of higher 2,3‑BPG. Assuming arterial oxygen content is given by \(C_{aO2}= (Hb\times1.34\times SaO2) + (0.0031\times PaO2)\) and that SaO₂ can be approximated by the Hill equation \(SaO2 = \frac{PaO2^{n}}{PaO2^{n}+P_{50}^{n}}\) with \(n = 2.7\), calculate the minimum increase in hemoglobin concentration (in g L⁻¹) required for the high‑altitude population to achieve the same arterial oxygen content as the sea‑level population.

Answer Options

Correct Answer A. Approximately 2 g L⁻¹ increase (about 1.7 g L⁻¹) in hemoglobin concentration is needed.
B. Approximately 5 g L⁻¹ increase (about 4.8 g L⁻¹) in hemoglobin concentration is needed.
C. Approximately 0.5 g L⁻¹ increase (about 0.4 g L⁻¹) in hemoglobin concentration is needed.
D. Approximately 10 g L⁻¹ increase (about 9.5 g L⁻¹) in hemoglobin concentration is needed.
Correct Answer
A
Correct Option:
Approximately 2 g L⁻¹ increase (about 1.7 g L⁻¹) in hemoglobin concentration is needed.

About This Question

This is Neco Model Questions Vol1 2019 Biology Question 33. It is one of the objective questions from the 2019 Neco Model Questions Vol1 Biology examination.

Difficulty level: Hard .

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