Neco 2025 Biology Question 7

Practice essay / theory question 7 from the 2025 Neco Biology examination. This question covers Homeostasis .

Neco 2025 Biology Essay / Theory
Topic: Homeostasis
Question 7 NECO • 2025 • BIOLOGY • essay

A 45-year-old man with a known defect in pancreatic β‑cells attends the clinic for a routine check‑up. After consuming a standard carbohydrate‑rich meal, his fasting blood glucose rises from 5.0 mmol/L to 9.0 mmol/L. In a normal individual, insulin secretion (µU/mL) can be approximated by the linear relation: Insulin = 10 × (Glucose – 4). The patient’s β‑cells secrete only 30 % of the insulin that a normal pancreas would produce under the same glucose concentration. Assume that glucose uptake by peripheral tissues is directly proportional to the plasma insulin concentration. Answer the following:

Question Parts

( a )
Describe the negative feedback mechanism that regulates blood glucose concentration. Identify the sensory receptor, integrating centre and effector organs involved.
( b )
Calculate: (i) The expected plasma insulin concentration in a normal individual when his post‑prandial glucose is 9.0 mmol/L. (ii) The actual insulin concentration in this patient. (iii) The percentage reduction in glucose uptake by peripheral tissues compared with a normal individual, assuming uptake is directly proportional to insulin concentration.
( c )
Discuss two possible long‑term health consequences of this impaired glucose homeostasis and suggest two lifestyle interventions that could help mitigate these effects.

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About This Question

This is Neco 2025 Biology Question 7. It is one of the essay questions from the 2025 Neco Biology examination.

The question covers Homeostasis .

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