Neco 2018 Biology Question 2
Practice objective / multiple choice question 2 from the 2018 Neco Biology examination.
A bacterial strain has a spontaneous mutation rate to resistance against antibiotic X of \(2\times10^{-8}\) per cell division. After 12\,h of growth the culture contains \(5\times10^{9}\) cells. The minimum inhibitory concentration (MIC) for the wild‑type is 4\,\(\mu\)g\,mL\(^{-1}\) and for resistant mutants is 16\,\(\mu\)g\,mL\(^{-1}\). The clinician wants to use a single concentration of antibiotic X that will inhibit at least 99\% of the total population. What is the minimum concentration that should be administered, taking into account the probability that resistant mutants are present?
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About This Question
This is Neco 2018 Biology Question 2. It is one of the objective questions from the 2018 Neco Biology examination.
Difficulty level: Hard .
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