Gce Model Questions Vol1 2025 Biology Question 6

Practice essay / theory question 6 from the 2025 Gce Model Questions Vol1 Biology examination. This question covers Excretion, Kidney function, Glomerular filtration, Urine concentration, Counter‑current multiplication .

Gce Model Questions Vol1 2025 Biology Essay / Theory
Topics: Excretion Kidney function Glomerular filtration Urine concentration Counter‑current multiplication
Question 6 GCE_MODEL_QUESTIONS_VOL1 • 2025 • BIOLOGY • essay

A 25‑year‑old adult has the following laboratory results: - Plasma creatinine concentration = 0.9 mg dL⁻¹ - Urine creatinine concentration = 90 mg dL⁻¹ - 24‑hour urine volume = 1.5 L Using these data, answer the following: a) Estimate the creatinine clearance (in mL min⁻¹) and explain why it is used as an approximation of the glomerular filtration rate (GFR). b) Describe the counter‑current multiplication mechanism in the loop of Henle and explain how it enables the kidney to produce urine that is more concentrated than plasma. Include in your answer the roles of the descending and ascending limbs.

Question Parts

( a )
Estimate the creatinine clearance (in mL min⁻¹) and explain why it is used as an approximation of the glomerular filtration rate (GFR).
( b )
Describe the counter‑current multiplication mechanism in the loop of Henle and explain how it enables the kidney to produce urine that is more concentrated than plasma. Include in your answer the roles of the descending and ascending limbs.

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About This Question

This is Gce Model Questions Vol1 2025 Biology Question 6. It is one of the essay questions from the 2025 Gce Model Questions Vol1 Biology examination.

The question covers Excretion, Kidney function, Glomerular filtration, Urine concentration, Counter‑current multiplication .

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