Gce Model Questions Vol1 2021 Biology Question 10

Practice essay / theory question 10 from the 2021 Gce Model Questions Vol1 Biology examination. This question covers Genetics .

Gce Model Questions Vol1 2021 Biology Essay / Theory
Topic: Genetics
Question 10 GCE_MODEL_QUESTIONS_VOL1 • 2021 • BIOLOGY • essay

Understanding inheritance patterns is essential for predicting genetic disorders.

Question Parts

( a )
A pedigree shows a rare autosomal recessive disorder. In the pedigree, two unaffected parents have an affected child. Explain how this observation supports autosomal recessive inheritance, and calculate the probability that two of their unaffected siblings will both be carriers, assuming Hardy‑Weinberg equilibrium with allele frequency q = 0.02 in the population.
( b )
A scientist uses PCR to amplify a specific gene segment before sequencing. Outline the steps of PCR, then explain how the choice of annealing temperature influences specificity and yield of the product.
( c )
Gene therapy aims to correct a defective gene in somatic cells. Discuss two major ethical concerns associated with somatic gene therapy, and suggest one regulatory measure to address each concern.

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About This Question

This is Gce Model Questions Vol1 2021 Biology Question 10. It is one of the essay questions from the 2021 Gce Model Questions Vol1 Biology examination.

The question covers Genetics .

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