Ijmb Model Questions Vol1 2022 Biology Question 9

Practice essay / theory question 9 from the 2022 Ijmb Model Questions Vol1 Biology examination. This question covers Reproduction .

Ijmb Model Questions Vol1 2022 Biology Essay / Theory

Topic: Reproduction

Question 9 IJMB_MODEL_QUESTIONS_VOL1 • 2022 • BIOLOGY • essay

A 28‑year‑old woman presents with secondary amenorrhoea. Laboratory results show: FSH 3 IU/L, LH 2 IU/L, estradiol 30 pg/mL, prolactin 8 µg/L. MRI reveals a 6‑mm pituitary microadenoma. She reports regular menstrual cycles before the past eight months.

Question Parts

( a )

Explain the normal hormonal feedback mechanisms that regulate the menstrual cycle, indicating the phases in which FSH, LH and estradiol reach their peak concentrations.

( b )

Using the data provided, deduce the most likely site of dysfunction in the reproductive axis and justify your answer.

( c )

Predict the effect of surgical removal of the microadenoma on the hormone profile and menstrual pattern.

( d )

If the patient is treated with a continuous‑release GnRH agonist pump, describe the expected changes in FSH, LH and estradiol concentrations over the first four weeks and explain the clinical rationale.

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About This Question

This is Ijmb Model Questions Vol1 2022 Biology Question 9. It is one of the essay questions from the 2022 Ijmb Model Questions Vol1 Biology examination.

The question covers Reproduction .

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